A pulmonary embolus is most often caused by a blood clot in a vein. The most common blood clot is one in a deep vein of the thigh or in the pelvis (hip area). This type of clot is called a deep vein thrombosis (DVT). The blood clot breaks off and travels to the lungs.
Less common causes include air bubbles, fat droplets, amniotic fluid, or clumps of parasites or tumor cells.
You are more likely to get this condition if you or your family have a history of blood clots or certain clotting disorders. A pulmonary embolus may occur:
After heart attack, heart surgery, or stroke
After severe injuries, burns, or fractures of the hips or thigh bone
After surgery, most commonly bone, joint, or brain surgery
During or after a long plane or car ride
If you have cancer
If you take birth control pills or estrogen therapy
Long-term bed rest or staying in one position for a long time
Main symptoms include chest pain that may be any of the following:
Under the breastbone or on one side
Sharp or stabbing
Burning, aching, or dull, heavy sensation
Usually gets worse with deep breathing
You may bend over or hold your chest in response to the pain
Other symptoms may include:
Bluish skin (cyanosis)
Dizziness, lightheadedness, or fainting
Fast breathing or wheezing
Fast heart rate
Leg pain, redness, or swelling
Low blood pressure
Sudden cough, possibly coughing up blood or bloody mucus
Shortness of breath that starts suddenly
Sweating, clammy skin
Exams and Tests
The health care provider will perform a physical exam and ask about your symptoms and medical history.
The following lab tests may be done to see how well your lungs are working:
A pulmonary embolus requires treatment right away. You may need to stay in the hospital:
You will receive medicines to thin the blood (to make it less likely your blood will form more clots).
In cases of severe, life-threatening pulmonary embolism, treatment may involve dissolving the clot. This is called thrombolytic therapy. You will receive medicines to dissolve the clot.
Whether or not you need to stay in the hospital, you will likely need to take medicines at home to thin the blood:
You may be given pills to take or you may need to give yourself injections.
For some medicines, you will need blood tests to monitor your dosage.
How long you need to take these medicines depends mostly on the cause and size of your blood clot.
Your health care provider will talk to you about the risk of bleeding problems when you take these medicines.
If you cannot take blood thinners, your doctor may suggest surgery to place a device called an inferior vena cava filter (IVC filter). This device is placed in the main vein in your belly. It keeps large clots from traveling into the blood vessels of the lungs. Sometimes a temporary filter can be placed and removed later.
How well a person recovers from a pulmonary embolus can be hard to predict. It often depends on:
What caused the problem in the first place (for example, cancer, major surgery, or an injury)
The size of the blood clot in the lungs
If the blood clot dissolves over time
Some people can develop long-term heart and lung problems.
Death is possible in people with a severe pulmonary embolism.
When to Contact a Medical Professional
Go to the emergency room or call the local emergency number (such as 911) if you have symptoms of pulmonary embolus.
Blood thinners may be prescribed to help prevent DVT in people at high risk, or those who are undergoing high-risk surgery.
If you had a DVT, your doctor will prescribe pressure stockings. Wear them as instructed. They will improve blood flow in your legs and reduce your risk of blood clots.
Moving your legs often during long plane trips, car trips, and other situations in which you are sitting or lying down for long periods can also help prevent DVT. People at very high risk of blood clots may need shots of a blood thinner called heparin when they take a flight that lasts longer than 4 hours.
Do not smoke. If you smoke, quit. Women who are taking estrogen must stop smoking.
Guyatt GH, Akl EA, Crowther M, et al. Executive summary: antithrombotic therapy and prevention of thrombosis, 9th ed. American College of Chest Physicians evidence-based clinical practice guidelines. Chest. 2012;141(2suppl):7s-47s.
Allen J. Blaivas, DO, Clinical Assistant Professor of Medicine UMDNJ-NJMS, Attending Physician in the Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Veteran Affairs, VA New Jersey Health Care System, East Orange, NJ. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.