Congenital antithrombin III deficiency is a genetic disorder that causes the blood to clot more than normal.
Deficiency - antithrombin III - congenital; Antithrombin III deficiency - congenital
People will usually have symptoms of a blood clot, including:
Coughing up blood
Shortness of breath and pain when taking deep breaths
Swelling of one leg
Exams and Tests
A physical exam may show:
Abnormal lung sounds
Fast heart rate
Swollen foot or leg
The doctor will check for low blood level of antithrombin III. There are different methods for checking this level.
A blood clot is treated with blood thinning medications (also called anticoagulants). How long you need to take these medications depends on how serious the blood clot was and other factors. Discuss this with your health care provider.
Most patients have a good outcome if they stay on anticoagulant medications.
When to Contact a Medical Professional
See your health care provider if you have symptoms of this condition.
Anderson JA, Weitz JI. Hypercoagulable states. In: Hoffman R, Benz EJ Jr, Silberstein LE, Heslop HE, Weitz JI, eds. Hematology: Basic Principles and Practice. 6th ed. Philadelphia, PA: Saunders Elsevier; 2012:chap 142.