Campylobacter serology test is a blood test to look for antibodies to a bacteria called campylobacter.
How the Test is Performed
A blood sample is needed.
The sample is sent to a lab. There, tests are done to look for antibodies to campylobacter. Antibody production increases during the infection. When the illness first starts, few antibodies are detected. For this reason, blood tests need to be repeated 10 days to 2 weeks later.
How to Prepare for the Test
There is no special preparation.
How the Test will Feel
When the needle is inserted to draw blood, some people feel moderate pain. Others feel only a prick or stinging. Afterward, there may be some throbbing or a slight bruise. This soon goes away.
Why the Test is Performed
This test is used to detect the presence of antibodies to campylobacter in the blood. Campylobacter infection can cause diarrheal illness. A blood test is rarely done to diagnose campylobacter diarrheal illness. It is used if your doctor thinks you are having complications from this infection, such as reactive arthritis or Guillain-Barre syndrome.
No antibodies to campylobacter are present.
Normal value ranges may vary slightly among different laboratories. Talk to your doctor about the meaning of your specific test results.
What Abnormal Results Mean
An abnormal (positive) result means that antibodies against campylobacter have been detected. This means you have come in contact with the bacteria.
Tests are often repeated during the course of an illness to detect a rise in antibody levels. This rise helps to confirm an active infection. A low level may be a sign of a previous infection rather than current disease.
Veins and arteries vary in size from one patient to another and from one side of the body to the other. Obtaining a blood sample from some people may be more difficult than from others.
Other risks associated with having blood drawn are slight but may include:
Fainting or feeling light-headed
Hematoma (blood accumulating under the skin)
Infection (a slight risk any time the skin is broken)
Allos BM, Blaser MJ. Campylobacter jejuni and related species. In: Mandell GL, Bennett JE, Dolin R, eds. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. 7th ed. Philadelphia, PA: Elsevier Churchill Livingstone: 2009:chap 216.
Hall GS, Woods GL. Medical bacteriology. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. 22nd ed. Philadelphia, PA: Elsevier Saunders; 2011:chap 57.
Jatin M. Vyas, MD, PhD, Assistant Professor in Medicine, Harvard Medical School; Assistant in Medicine, Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital, Boston, MA. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.